Fig. 1 · Structure

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A-228839

Farnesyltransferase Inhibitor

A-228839 is a potent inhibitor of farnesyltransferase, a crucial enzyme involved in protein prenylation. By targeting this enzyme, A-228839 effectively inhibits lymphocyte activation and cytokine production. This compound is valuable for research applications in understanding T-cell signaling and potential therapeutic strategies for autoimmune diseases and cancer.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 216234-25-2
Applications Farnesyltransferase Inhibitor
Formula C32H45LiN2O3S
Molecular Weight 544.72
SMILES
CSCC[C@@H](C(O[Li])=O)NC(C1=CC=C(CN(CCCC)CCC2CCCCC2)C=C1C3=CC=CC=C3C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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