A-62198 is a selective renin inhibitor that exhibits significant antihypertensive properties. It effectively reduces mean arterial pressure (MAP) in anesthetized, salt-deprived primate models in a dose-dependent manner. Notably, A-62198 also demonstrates a statistically significant decrease in plasma renin activity (PRA) across all administered doses, making it a valuable tool for research in cardiovascular pharmacology and hypertension studies.
A-62198 is a selective renin inhibitor that exhibits significant antihypertensive properties. It effectively reduces mean arterial pressure (MAP) in anesthetized, salt-deprived primate models in a dose-dependent manner. Notably, A-62198 also demonstrates a statistically significant decrease in plasma renin activity (PRA) across all administered doses, making it a valuable tool for research in cardiovascular pharmacology and hypertension studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
