α-Amylase-IN-13 is a selective inhibitor of α-amylase that operates via a mixed inhibition mechanism (IC50 = 0.71 μM). This brain-penetrant compound has demonstrated the ability to significantly lower blood glucose levels in diabetic rat models and promotes notable histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 is a valuable tool for investigating diabetic complications and evaluating therapeutic strategies for diabetes management.
α-Amylase-IN-13 is a selective inhibitor of α-amylase that operates via a mixed inhibition mechanism (IC50 = 0.71 μM). This brain-penetrant compound has demonstrated the ability to significantly lower blood glucose levels in diabetic rat models and promotes notable histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 is a valuable tool for investigating diabetic complications and evaluating therapeutic strategies for diabetes management.
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