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α,δ-NAG

G protein-Coupled Receptor (GPCR) Allosteric Modulator

α,δ-NAG is an allosteric modulator targeting G protein-coupled receptors (GPCRs). This orally active derivative of L-Glutamine is resistant to glutaminase activity and exhibits less hydrolysis, making it a valuable tool in the study of inflammatory responses. α,δ-NAG effectively suppresses neutrophilic airway inflammation by activating the GPCR/ERK/MKP-1 signaling pathway. This compound is useful for research applications in inflammation and immunology, particularly in conditions such as asthma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	3051899-13-6
Applications	G protein-Coupled Receptor (GPCR) Allosteric Modulator
Formula	C₉H₁₄N₂O₅
Molecular Weight	230.22
SMILES	O=C(NC(C)=O)CC[C@H](C(O)=O)NC(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.