Fig. 1 · Structure
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α-Glucosidase-IN-68
Cat. No.
A75186
CAS
1624628-01-8
α-Glucosidase Inhibitor
α-Glucosidase-IN-68 is a selective inhibitor of α-glucosidase, demonstrating an IC50 of 0.251 μM, along with inhibition of AChE and BChE at 0.774 μM and 0.793 μM, respectively. This compound exhibits strong antioxidant properties, with IC50 values of 0.69 μM in the DPPH assay and 0.02 μM in the ABTS assay. Additionally, α-Glucosidase-IN-68 has been shown to have an antidiabetic effect in streptozotocin-induced diabetic rat models, making it a valuable tool for research in diabetes and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1624628-01-8 |
| Applications | α-Glucosidase Inhibitor |
| Formula | C32H26F4N2O2 |
| Molecular Weight | 546.55 |
| SMILES | O=C(C1=C(NC2=CC=C(F)C=C2)CC(C3=CC=C(F)C=C3)N(C4=CC=C(F)C=C4)C1C5=CC=C(F)C=C5)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.