Fig. 1 · Structure
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α-Synuclein aggregate binder 1
α-Synuclein Aggregate Inhibitor
α-Synuclein aggregate binder 1 is a selective inhibitor of α-synuclein aggregation, targeting pathological fibril formation associated with neurodegenerative diseases. This compound serves as a fluorescent probe for optical imaging, with an excitation wavelength of 900 nm and a detection range of 500-550 nm. Additionally, it can be labeled with 18F for use in positron emission tomography (PET) imaging, facilitating visual diagnosis of brain lesions and advancing research into the mechanisms underlying conditions like Parkinson's disease and Lewy body dementia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1565797-17-2 |
| Applications | α-Synuclein Aggregate Inhibitor |
| Formula | C20H18FN3O2S |
| Molecular Weight | 383.44 |
| SMILES | CNC1=NC=C(C=C1)C#C/C=C/C(SC2=C3)=NC2=CC=C3OCC(O)CF |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.