A924 is an amino acid derivative that functions as an orally active antitumor agent. It demonstrates efficacy in inhibiting ascites tumors in rat models, employing both intraperitoneal injection and oral administration routes. With an LD50 of greater than 1.5 g/kg via intraperitoneal injection and over 4.5 g/kg through oral administration in mice, A924 exhibits a favorable safety profile, showing no teratogenic effects or adverse reactions in normal or pregnant mice. This compound is valuable for research applications focused on cancer treatment and mechanism studies.
A924 is an amino acid derivative that functions as an orally active antitumor agent. It demonstrates efficacy in inhibiting ascites tumors in rat models, employing both intraperitoneal injection and oral administration routes. With an LD50 of greater than 1.5 g/kg via intraperitoneal injection and over 4.5 g/kg through oral administration in mice, A924 exhibits a favorable safety profile, showing no teratogenic effects or adverse reactions in normal or pregnant mice. This compound is valuable for research applications focused on cancer treatment and mechanism studies.
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