Fig. 1 · Structure
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AA10
TG2 Inhibitor
AA10 is a potent and irreversible inhibitor of transglutaminase 2 (TG2), an enzyme implicated in various cancer-related processes. This compound demonstrates significant biological activity in inhibiting TG2-mediated pathways, making it a valuable tool for cancer research. AA10 is suitable for studies investigating the role of TG2 in tumor progression and metastasis and may aid in the development of targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2134106-02-6 |
| Applications | TG2 Inhibitor |
| Formula | C32H36N4O5 |
| Molecular Weight | 556.65 |
| SMILES | O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=CC=C4C=CC=CC4=C3)=O)CC2)=O)CCCCNC(C=C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.