Fig. 1 · Structure

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AAL-149

Cat. No. A68793 CAS 177258-60-5

TRPM7 Inhibitor

AAL-149 is a selective inhibitor of the TRPM7 ion channel, exhibiting an IC50 value of 1.081 μM. This compound demonstrates multimodal anti-inflammatory effects while avoiding interaction with sphingosine-1-phosphate (S1P) receptors. AAL-149 is a valuable tool for researchers investigating the role of TRPM7 in inflammation and related biological pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 177258-60-5
Applications TRPM7 Inhibitor
Formula C18H31NO2
Molecular Weight 293.44
SMILES
N[C@@](CO)(C)CCC1=CC=C(OCCCCCCC)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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