ABBV-744

Catalog No.: A16831

BET bromodomain inhibitor

ABBV-744

ABBV-744 Chemical Structure

CAS NO. 2138861-99-9

ABBV-744 is a BDII-selective BET bromodomain inhibitor that is being investigated to treat AML and metastic castration-resistant prostate cancer.

Availability: In stock

Package Price Qty
2 mg
$70.00
5 mg
$110.00
10 mg
$175.00
50 mg
$500.00
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Biological Activity

ABBV-744 is a BDII-selective BET bromodomain inhibitor that is being investigated to treat AML and metastic castration-resistant prostate cancer.
In vitro DMSO 94 mg/mL (191.22 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.34 mL 101.72 mL 203.44 mL
0.5 mM 4.07 mL 20.34 mL 40.69 mL
1 mM 2.03 mL 10.17 mL 20.34 mL
5 mM 0.41 mL 2.03 mL 4.07 mL

*The above data is based on the productmolecular weight 491.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16831
Actions Inhibitor
CAS No. 2138861-99-9
Formula C28H30FN3O4
M. Wt 491.55
Solubility DMSO
Purity >98%
Synonyms ABBV 744, ABBV744
SMILES O=C(C(N1)=CC(C(C2=CC(C(C)(O)C)=CC=C2OC3=C(C)C=C(F)C=C3C)=CN4C)=C1C4=O)NCC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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