Fig. 1 · Structure
Documents & Downloads
ABC44
Serine Hydrolase Inhibitor
ABC44 is a potent serine hydrolase inhibitor that demonstrates IC50 values of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. This compound is valuable for investigating the mechanisms underlying infantile neuronal ceroid lipofuscinosis and may aid in the development of therapeutic strategies for this condition. Researchers can utilize ABC44 to better understand the role of PPT1 in neurodegenerative diseases.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1831135-46-6 |
| Applications | Serine Hydrolase Inhibitor |
| Formula | C31H40N6O5 |
| Molecular Weight | 576.69 |
| SMILES | O=C(N1CCN(C2=CC=C(OC)C=C2)CC1)ON(C3=O)C(N4C3CN(CC5CCN(CC6=CC=CC=C6)CC5)CC4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.