Fig. 1 · Structure
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ABCA1 inducer 1
ABCA1 Inducer
ABCA1 Inducer 1 is a potent inducer of the ATP-binding cassette transporter A1 (ABCA1). It effectively increases ABCA1 expression and enhances the lipidation of apolipoprotein E (APOE), contributing to the reversal of multiple Alzheimer's disease phenotypes. Notably, this compound operates without elevating triglyceride levels in E3/4FAD mice expressing human APOE 3/4, making it a valuable tool for research into Alzheimer’s disease and lipid metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 2839627-76-6 |
| Applications | ABCA1 Inducer |
| Formula | C24H24Cl2N2O7S2 |
| Molecular Weight | 587.49 |
| SMILES | CCOC(C1=CC(NC(C2=C(C=C(S2)Cl)S(=O)(N(C3=CC(OC)=C(C=C3)OCC)C)=O)=O)=CC(Cl)=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.