Fig. 1 · Structure
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ABD-1970
MAGL Inhibitor
ABD-1970 is a selective monoacylglycerol lipase (MAGL) inhibitor, exhibiting IC50 values of 15 nM for human MAGL and 29 nM for mouse MAGL. This compound demonstrates a strong preference for MGLL over other serine hydrolases, making it a valuable tool for research. ABD-1970 has potential applications in the study of neurological disorders, providing insights into endogenous cannabinoid signaling pathways and related therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2010154-82-0 |
| Applications | MAGL Inhibitor |
| Formula | C21H24ClF6N3O3 |
| Molecular Weight | 515.88 |
| SMILES | O=C(N1CCN(CC2=CC=C(Cl)C=C2N3CC(O4)CCC4C3)CC1)OC(C(F)(F)F)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.