Fig. 1 · Structure

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AC-42 hydrochloride

AC 42 is an allosteric agonist.

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Biological Activity

Cellular Effect

Cell Line Activity Value Description Reference
HEK293 EC50 0.21 μM Partial agonist activity at EGFP-fused human full length M1 receptor expressed in HEK293 cells assessed as induction of calcium response by fluorescence assay [PMID: 22329602]
HEK293 EC50 0.45 μM Partial agonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as induction of calcium response by fluorescence assay [PMID: 22329602]
HEK293 EC50 0.72 μM Partial agonist activity at EGFP-fused human M1 receptor N-terminal truncated at 11 residues expressed in HEK293 cells assessed as induction of calcium response by fluorescence assay [PMID: 22329602]
HEK293 EC50 0.74 μM Partial agonist activity at human full length M1 receptor expressed in HEK293 cells assessed as induction of calcium response by fluorescence assay [PMID: 22329602]

Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 447407-36-5
Formula C20H31NO.ClH
Molecular Weight 337.932
Synonyms AC 42
SMILES
CCCCC1CCN(CC1)CCCC(=O)C2=CC=CC=C2C.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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