Ac-Asp-Glu-Val-Asp-pNA is a specific substrate for caspase-3/7, facilitating the study of apoptosis and cellular signaling pathways. This peptidic compound is cleaved by caspase-3/7, resulting in the release of p-nitroaniline (pNA), which can be quantitatively measured. Its use is critical in research applications focused on understanding programmed cell death and evaluating the activity of caspases in various biological contexts.
Ac-Asp-Glu-Val-Asp-pNA is a specific substrate for caspase-3/7, facilitating the study of apoptosis and cellular signaling pathways. This peptidic compound is cleaved by caspase-3/7, resulting in the release of p-nitroaniline (pNA), which can be quantitatively measured. Its use is critical in research applications focused on understanding programmed cell death and evaluating the activity of caspases in various biological contexts.
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