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Ac-DMQD-CHO

Catalog No.: A25352
Caspase Inhibitor
Ac-DMQD-CHO is a selective inhibitor of caspase 3, exhibiting an IC50 of 39 nM. This compound effectively reduces apoptosis, making it a valuable tool in studies related to neuroprotection and cellular survival. Its application in research can aid in the exploration of therapeutic strategies targeting neurodegenerative diseases and apoptosis-related conditions.
Ac-DMQD-CHO 259199-63-8 Caspase Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAc-DMQD-CHO is a selective inhibitor of caspase 3, exhibiting an IC50 of 39 nM. This compound effectively reduces apoptosis, making it a valuable tool in studies related to neuroprotection and cellular survival. Its application in research can aid in the exploration of therapeutic strategies targeting neurodegenerative diseases and apoptosis-related conditions.
Product Information
Catalog NumA25352
FormulaC20H31N5O10S
Molecular Weight533.55
CAS Number259199-63-8
SequenceAc-Asp-Met-Gln-Asp-CHO
Sequence shorteningAc-DMQD-CHO
SMILES[C@@H](NC([C@@H](NC([C@H](CC(O)=O)NC(C)=O)=O)CCSC)=O)(C(N[C@@H](CC(O)=O)C=O)=O)CCC(N)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Apoptosis > Caspase
Proteases > Caspase