Fig. 1 · Structure

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Ac-EEVVAC-pNA

Chromogenic Substrate

Ac-EEVVAC-pNA is a chromogenic substrate specifically designed for continuous spectrophotometric assays targeting Hepatitis C Virus (HCV) NS3 protease. The substrate sequence, EEVVAC, is derived from the cleavage junction of the HCV polyprotein, facilitating the study of protease activity. Its use in biochemical assays enables researchers to investigate HCV protease mechanisms and develop potential therapeutic strategies against the virus.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 389868-12-6
Applications Chromogenic Substrate
Formula C34H50N8O13S
Molecular Weight 810.87
SMILES
CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)Nc1ccc(cc1)N(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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