Ac-VAD-pNA

Catalog No.: A25204
Caspase-1 Substrate
Ac-VAD-pNA is a synthetic substrate specifically designed for the detection of caspase-1 activity. This compound enables the assessment of caspase-1 enzymatic function, making it a valuable tool for studying apoptotic and inflammatory pathways. Its utility in various research applications includes investigating mechanisms of cell death and inflammatory responses, facilitating advancements in therapeutic strategies targeting these processes.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAc-VAD-pNA is a synthetic substrate specifically designed for the detection of caspase-1 activity. This compound enables the assessment of caspase-1 enzymatic function, making it a valuable tool for studying apoptotic and inflammatory pathways. Its utility in various research applications includes investigating mechanisms of cell death and inflammatory responses, facilitating advancements in therapeutic strategies targeting these processes.
Product Information
Catalog NumA25204
FormulaC20H27N5O8
Molecular Weight465.46
CAS Number154564-07-5
SequenceAc-Val-Ala-Asp-pNA
Sequence shorteningAc-VAD-pNA
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2