Acetaminophen

Catalog No.: A10030

COX inhibitor

Acetaminophen

Acetaminophen Chemical Structure

CAS NO. 103-90-2

Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

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100 mg
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250 mg
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500 mg
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1000 mg
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  • Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
  • Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
  • Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

Biological Activity

Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 66.16 mL 330.78 mL 661.55 mL
0.5 mM 13.23 mL 66.16 mL 132.31 mL
1 mM 6.62 mL 33.08 mL 66.16 mL
5 mM 1.32 mL 6.62 mL 13.23 mL

*The above data is based on the productmolecular weight 151.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10030
Actions Inhibitor
M. Wt 151.16
Formula C8H9NO2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 103-90-2
Synonyms Paracetamol
SMILES CC(=O)NC1=CC=C(C=C1)O

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