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AChE/BChE-IN-11

AChE/BChE Inhibitor

AChE/BChE-IN-11 is a potent dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 70 μM and 71 μM, respectively. This natural product, derived from artichoke leaves, exhibits significant biological activity relevant to neurodegenerative disorders. AChE/BChE-IN-11 can be utilized in studies investigating Alzheimer's disease and other conditions linked to cholinergic dysfunction, facilitating the exploration of therapeutic options targeting cholinesterase enzymes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	80443-12-5
Applications	AChE/BChE Inhibitor
Formula	C₂₁H₂₂O₁₂
Molecular Weight	466.39
SMILES	OC1=CC(O)=C2C(O[C@H](C3=CC(O)=C(O)C(O)=C3)[C@@H](O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C2=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.