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AChE/BChE-IN-19

AChE/BChE Inhibitor

AChE/BChE-IN-19 is a nicotinic hydrazide derivative that acts as an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 21.45 nM and 18.42 nM, respectively. This compound is particularly relevant for studies investigating cholinergic dysfunction in neurodegenerative diseases, such as Alzheimer's disease. Its potent inhibitory activity makes it a valuable tool for exploring therapeutic strategies targeting cholinergic pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3036136-22-5
Applications	AChE/BChE Inhibitor
Formula	C₂₆H₂₂N₄O₃
Molecular Weight	438.48
SMILES	O=C(N/N=C/C1=C(C=CC=C2)C2=CC=C1OC(C3=CC=C(N(C)C)C=C3)=O)C4=CN=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.