Fig. 1 · Structure
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AChE/BChE-IN-2
AChE/BChE Inhibitor
AChE/BChE-IN-2 is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting IC50 values of 0.96 ± 0.14 µM for AChE and 1.23 ± 0.23 µM for BChE. This compound is valuable for research into Alzheimer's disease and other neurodegenerative disorders, facilitating studies on cholinergic signaling and enzyme activity modulation. Its efficacy in inhibiting cholinesterases makes it a significant tool for understanding the biochemical pathways involved in cognitive decline.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2761991-42-6 |
| Applications | AChE/BChE Inhibitor |
| Formula | C23H25N3O5 |
| Molecular Weight | 423.46 |
| SMILES | O=C(NCC(NCCC1=CNC2=C1C=C(OC)C=C2)=O)/C=C/C3=CC=C(O)C(OC)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.