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AChE-IN-10

AChE Inhibitor

AChE-IN-10 is a highly effective inhibitor of acetylcholinesterase (AChE), with an IC50 value of 2.4 nM. This compound demonstrates significant neuroprotective effects by enhancing neuronal morphology and increasing cell viability, while also reducing tau phosphorylation at the S396 residue. Additionally, AChE-IN-10 has been shown to decrease amyloid aggregation in conjunction with AChE activity, making it a valuable tool for research in neurodegenerative diseases and cognitive disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770832-90-9
Applications	AChE Inhibitor
Formula	C₂₃H₂₇F₂NO₄S
Molecular Weight	451.53
SMILES	COC1=C(C=C2C(CC(CC3CCN(CC3)CC4=CC=CC(F)=C4)(S2(=O)=O)F)=C1)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.