AChE-IN-10 is a highly effective inhibitor of acetylcholinesterase (AChE), with an IC50 value of 2.4 nM. This compound demonstrates significant neuroprotective effects by enhancing neuronal morphology and increasing cell viability, while also reducing tau phosphorylation at the S396 residue. Additionally, AChE-IN-10 has been shown to decrease amyloid aggregation in conjunction with AChE activity, making it a valuable tool for research in neurodegenerative diseases and cognitive disorders.
AChE-IN-10 is a highly effective inhibitor of acetylcholinesterase (AChE), with an IC50 value of 2.4 nM. This compound demonstrates significant neuroprotective effects by enhancing neuronal morphology and increasing cell viability, while also reducing tau phosphorylation at the S396 residue. Additionally, AChE-IN-10 has been shown to decrease amyloid aggregation in conjunction with AChE activity, making it a valuable tool for research in neurodegenerative diseases and cognitive disorders.
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