Fig. 1 · Structure
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AChE-IN-103
Ach Inhibitor
AChE-IN-103 is a potent acetylcholinesterase (AChE) inhibitor that demonstrates log IC50 values of 1.477 and 2.2 in alignment models I and II, respectively. This compound plays a significant role in the research of Alzheimer’s disease, where it may help elucidate the mechanisms of cholinergic dysfunction. AChE-IN-103 is valuable for studies aimed at developing therapeutic strategies targeting cognitive decline associated with this neurodegenerative disorder.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 113027-75-1 |
| Applications | Ach Inhibitor |
| Formula | C22H24N2O2 |
| Molecular Weight | 348.45 |
| SMILES | O=C1C=2C=CC=CC2C(=O)N1CCC3CCN(CC=4C=CC=CC4)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.