AChE-IN-36

Catalog No.: A78807
Acetylcholinesterase inhibitor
AChE-IN-36 is a potent inhibitor of acetylcholinesterase, exhibiting an IC50 of 0.04 μM. This compound influences reactive oxygen species (ROS) levels and modulates the gene expression of NRF2, making it a valuable tool for studies on neurodegenerative diseases and oxidative stress responses. Its activity is relevant for research focused on cholinergic signaling and cellular antioxidant pathways.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAChE-IN-36 is a potent inhibitor of acetylcholinesterase, exhibiting an IC50 of 0.04 μM. This compound influences reactive oxygen species (ROS) levels and modulates the gene expression of NRF2, making it a valuable tool for studies on neurodegenerative diseases and oxidative stress responses. Its activity is relevant for research focused on cholinergic signaling and cellular antioxidant pathways.
Product Information
Catalog NumA78807
FormulaC25H21ClO5S
Molecular Weight468.95
CAS Number2978753-66-9
SMILESO=S(C1=CC=C(C(C)(C)C)C=C1)(OC2=CC=C3C(/C(OC3=C2)=C/C4=CC=C(Cl)C=C4)=O)=O
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