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AChE-IN-41

Cholinesterase Inhibitor

AChE-IN-41 is a cholinesterase inhibitor designed to enhance acetylcholine levels by preventing its breakdown. This hybrid compound of Galantamine and Memantine demonstrates significant inhibition of cholinesterase activity, offering valuable insights for neurological research. AChE-IN-41 exhibits enhanced plasma stability and similar microsomal stability in vitro, although it possesses a shorter half-life and faster clearance in vivo, making it suitable for studies on cholinergic signaling and potential therapeutic applications in neurodegenerative diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3038811-77-4
Applications	Cholinesterase Inhibitor
Formula	C₃₂H₄₄N₂O₃
Molecular Weight	504.70
SMILES	O[C@H]1C=C[C@@]23C(C(CN(C/C=C/CN[C@@]45C[C@]6(C)C[C@@](C5)(C)C[C@@H](C6)C4)CC3)=CC=C7OC)=C7O[C@H]2C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.