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AChE-IN-47

AChE Inhibitor

AChE-IN-47 is a potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.24 μM. This compound effectively hinders the self-aggregation of amyloid β peptides, demonstrating neuroprotective properties. Additionally, AChE-IN-47 significantly reduces intracellular accumulation of reactive oxygen species, making it a valuable tool for research in neurodegenerative disease models and studies focused on oxidative stress.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033056-55-9
Applications	AChE Inhibitor
Formula	C₂₀H₁₇F₃N₄O₄S
Molecular Weight	466.43
SMILES	O=C(NC1=CC=C2C(N3CCCC3=NC2=C1)=O)CNS(=O)(C4=CC=CC=C4C(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.