Fig. 1 · Structure

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Acid-PEG25-NHS ester

PROTAC Linkers

Acid-PEG25-NHS ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates targeted protein degradation by optimizing the conjugation of various protein tags and ligands. Its use is pivotal in research applications aimed at exploring novel therapeutic strategies through protein modulation and degradation pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2563872-17-1
Applications PROTAC Linkers
Formula C58H109NO31
Molecular Weight 1316.47
SMILES
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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