Fig. 1 · Structure
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Acivicin hydrochloride
γ-glutamyl Transpeptidase Inhibitor
Acivicin hydrochloride is a potent inhibitor of γ-glutamyl transpeptidase (GGT), a key enzyme involved in amino acid transport and metabolism. This natural product, derived from Streptomyces sviceus, demonstrates notable anti-cancer and anti-parasitic activities. Due to its ability to cross the blood-brain barrier, Acivicin hydrochloride is also leveraged in research focusing on neurological disorders and tumor biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 161922-40-3 |
| Applications | γ-glutamyl Transpeptidase Inhibitor |
| Formula | C5H8Cl2N2O3 |
| Molecular Weight | 215.03 |
| Synonyms | AT-125 hydrochloride; U-42126 hydrochloride |
| SMILES | [H]Cl.ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.