Fig. 1 · Structure
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Acivicin
γ-glutamyl Transpeptidase Inhibitor
Acivicin is a potent inhibitor of γ-glutamyl transpeptidase (GGT), a key enzyme in glutathione metabolism. Derived from the natural product Streptomyces sviceus, Acivicin demonstrates significant anti-cancer and anti-parasitic activities. Its ability to cross the blood-brain barrier enhances its potential for applications in neurological and oncological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 42228-92-2 |
| Applications | γ-glutamyl Transpeptidase Inhibitor |
| Formula | C5H7ClN2O3 |
| Molecular Weight | 178.57 |
| Synonyms | AT-125; U-42126 |
| SMILES | ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.