ACY-775

Catalog No.: A12456

HDAC6 inhibitor

ACY-775

ACY-775 Chemical Structure

CAS NO. 1375466-18-4

ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5?nM.

Availability: In stock

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2 mg

Regular Price: $72.00

Special Price $57.60

5 mg

Regular Price: $144.00

Special Price $115.20

10 mg

Regular Price: $280.00

Special Price $224.00

50 mg

Regular Price: $824.00

Special Price $659.20

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Biological Activity

ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5?nM.
In vitro DMSO 63 mg/mL (190.7 mM)
Water Insoluble
Ethanol 63 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.27 mL 151.35 mL 302.7 mL
0.5 mM 6.05 mL 30.27 mL 60.54 mL
1 mM 3.03 mL 15.14 mL 30.27 mL
5 mM 0.61 mL 3.03 mL 6.05 mL

*The above data is based on the productmolecular weight 330.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12456
Actions Inhibitor
CAS No. 1375466-18-4
Formula C17H19FN4O2
M. Wt 330.36
Purity >98%
Synonyms ACY775, ACY 775
SMILES O=C(NO)C(C=N1)=CN=C1NC2(CCCCC2)C3=CC=CC(F)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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