Fig. 1 · Structure

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ADAM8-IN-1

ADAM8 Inhibitor

ADAM8-IN-1 is a selective inhibitor of the ADAM8 metalloproteinase, exhibiting an IC50 value of 73 nM. This compound is recognized for its role in modulating extracellular matrix remodeling and inflammatory processes. ADAM8-IN-1 is valuable for research applications focused on cancer biology, autoimmune diseases, and tissue remodeling, facilitating the study of ADAM8's involvement in various pathological conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2758892-64-5
Applications ADAM8 Inhibitor
Formula C44H44Br4N6O12S2
Molecular Weight 1232.60
SMILES
O=C(NCCC[C@@H](NS(=O)(C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1)=O)C(NO)=O)C3=CC=CC(C(NCCC[C@@H](NS(=O)(C4=CC=C(OCC5=CC(Br)=CC(Br)=C5)C=C4)=O)C(NO)=O)=O)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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