Adavivint
Wnt inhibitor
Important Notice: For research use only. We do not sell to patients.
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Wnt inhibitor
Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. |
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Catalog Num | A19257 |
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Formula | C29H24FN7O |
Molecular Weight | 505.55 |
CAS Number | 1467093-03-3 |
SMILES | CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN=C1)=O |
Synonyms | SM04690, SM 04690, SM-04690; Lorecivivint |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 30 mg/mL (59.34 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.78 mL | 98.9 mL | 197.8 mL |
0.5 mM | 3.96 mL | 19.78 mL | 39.56 mL |
1 mM | 1.98 mL | 9.89 mL | 19.78 mL |
5 mM | 0.4 mL | 1.98 mL | 3.96 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2