Fig. 1 · Structure

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Adefovir diphosphate

Cat. No. A73378 CAS 129556-87-2

Endogenous Metabolite

Adefovir diphosphate is a potent antiviral agent that targets hepatitis B virus (HBV) by inhibiting reverse transcriptase, thereby blocking viral replication. This compound is also active against other viruses, including herpes viruses and HIV. In research applications, Adefovir diphosphate is utilized for its effectiveness in suppressing chronic hepatitis B and may help reduce the risk of developing hepatocellular carcinoma (HCC) in affected patients through its mechanism that involves inhibiting the autophosphorylation of growth factor receptors.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 129556-87-2
Applications Endogenous Metabolite
Formula C8H13N5O7P2
Molecular Weight 353.17
SMILES
O=P(O)(OP(O)(COCCN1C=NC2=C1N=CN=C2N)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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