Adefovir diphosphate

Catalog No.: A73378
Endogenous Metabolite
Adefovir diphosphate is a potent antiviral agent that targets hepatitis B virus (HBV) by inhibiting reverse transcriptase, thereby blocking viral replication. This compound is also active against other viruses, including herpes viruses and HIV. In research applications, Adefovir diphosphate is utilized for its effectiveness in suppressing chronic hepatitis B and may help reduce the risk of developing hepatocellular carcinoma (HCC) in affected patients through its mechanism that involves inhibiting the autophosphorylation of growth factor receptors.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAdefovir diphosphate is a potent antiviral agent that targets hepatitis B virus (HBV) by inhibiting reverse transcriptase, thereby blocking viral replication. This compound is also active against other viruses, including herpes viruses and HIV. In research applications, Adefovir diphosphate is utilized for its effectiveness in suppressing chronic hepatitis B and may help reduce the risk of developing hepatocellular carcinoma (HCC) in affected patients through its mechanism that involves inhibiting the autophosphorylation of growth factor receptors.
Product Information
Catalog NumA73378
FormulaC8H13N5O7P2
Molecular Weight353.17
CAS Number129556-87-2
SMILESO=P(O)(OP(O)(COCCN1C=NC2=C1N=CN=C2N)=O)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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