Fig. 1 · Structure
Documents & Downloads
Adrogolide hydrochloride
A-86929 Prodrug
Adrogolide hydrochloride is a stable prodrug that converts to the dopamine D1 receptor agonist A-86929. It exhibits significant activity in attenuating the symptoms of Parkinson's disease in marmoset models, alleviating MPTP-induced motor impairments and reducing the risk of dyskinesias. Additionally, Adrogolide hydrochloride has demonstrated the ability to reverse cognitive deficits induced by Risperidone in non-human primate studies, making it a valuable tool for neurological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 166591-11-3 |
| Applications | A-86929 Prodrug |
| Formula | C22H26ClNO4S |
| Molecular Weight | 435.96 |
| Synonyms | ABT-431 hydrochloride; DAS-431 hydrochloride |
| SMILES | CCCC1=CC2=C(CN[C@@]3(CCC4=CC(OC(C)=O)=C(C=C4[C@@]23[H])OC(C)=O)[H])S1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.