Fig. 1 · Structure

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Adrogolide

A-86929 Prodrug

Adrogolide is a prodrug of A-86929, functioning as a selective agonist of the dopamine D1 receptor. Upon administration, Adrogolide is rapidly converted to A-86929 in the plasma, enhancing locomotor activity and improving behavioral outcomes. Additionally, it has been shown to reduce cocaine-seeking behavior, making it a valuable compound for research into the mechanisms underlying Parkinson's disease and addiction-related behaviors.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 171752-56-0
Applications A-86929 Prodrug
Formula C22H25NO4S
Molecular Weight 399.50
Synonyms ABT-431; DAS-431
SMILES
CC(OC1=C(OC(C)=O)C=C2CC[C@@]3([H])NCC(SC(CCC)=C4)=C4[C@]3([H])C2=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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