AE9C90CB

Catalog No.: A61517
M3 Muscarinic Receptor Antagonist
AE9C90CB is a selective antagonist of the M3 muscarinic receptor, exhibiting a high affinity with a pKi value of 9.90. This compound is 20-fold more selective for M3 compared to the M2 muscarinic receptor, making it a valuable tool for studying M3 receptor-mediated signaling pathways. AE9C90CB is suitable for research applications investigating the role of M3 muscarinic receptors in various physiological and pathological processes.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAE9C90CB is a selective antagonist of the M3 muscarinic receptor, exhibiting a high affinity with a pKi value of 9.90. This compound is 20-fold more selective for M3 compared to the M2 muscarinic receptor, making it a valuable tool for studying M3 receptor-mediated signaling pathways. AE9C90CB is suitable for research applications investigating the role of M3 muscarinic receptors in various physiological and pathological processes.
Product Information
Catalog NumA61517
FormulaC21H25ClN2O2
Molecular Weight372.89
CAS Number893426-98-7
SMILES[H][C@@]1(CNC2)[C@@]2([H])[C@H]1CN(C)C(C(C3=CC=CC=C3)(C4=CC=CC=C4)O)=O.Cl
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