AEOL-10150 pentachloride

Catalog No.: A38917
Metalloporphyrin Catalytic Antioxidant
AEOL-10150 pentachloride is a metalloporphyrin-catalyzed antioxidant that acts as a mimetic of superoxide dismutase. It effectively scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), while also modulating the NF-κB signaling pathway, demonstrating potent antioxidant and anti-inflammatory properties. This compound has been shown to reduce tissue damage from radiation and chemical agents, and it can enhance the effects of radiotherapy in targeting prostate tumors.
Grouped product items
Size Price Stock Qty
1mg
$70.00
In stock
5mg
$180.00
In stock
10mg
$300.00
In stock
25mg
$545.00
In stock
50mg
$810.00
In stock
100mg
$1,185.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAEOL-10150 pentachloride is a metalloporphyrin-catalyzed antioxidant that acts as a mimetic of superoxide dismutase. It effectively scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), while also modulating the NF-κB signaling pathway, demonstrating potent antioxidant and anti-inflammatory properties. This compound has been shown to reduce tissue damage from radiation and chemical agents, and it can enhance the effects of radiotherapy in targeting prostate tumors.
Product Information
Catalog NumA38917
FormulaC48H56Cl5MnN12
Molecular Weight1033.24
CAS Number286475-30-7
SMILESCC[N+](C=CN1CC)=C1C2=C(C=CC3=C(C(N4CC)=[N+](C=C4)CC)C5=[N]6C(C=C5)=C7C(N8CC)=[N+](C=C8)CC)[N-]3[Mn+3]96[N]%10=C2C=CC%10=C(C(N%11CC)=[N+](C=C%11)CC)C%12=CC=C7[N-]9%12.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-]
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