Swertianolin is a xanthone glycoside extracted from various plants within the Gentianaceae family, such as Gentiana campestris and Swertia punicea. It inhibits p38 phosphorylation and NF-κB activation, leading to reduced nitric oxide (NO) and reactive oxygen species (ROS) production. Swertianolin demonstrates potent anti-Helicobacter pylori activity, with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Additionally, it has been shown to modulate immune function in sepsis, making it applicable for research in Alzheimer's disease, hepatitis B, Helicobacter pylori infections, and sepsis.
Swertianolin is a xanthone glycoside extracted from various plants within the Gentianaceae family, such as Gentiana campestris and Swertia punicea. It inhibits p38 phosphorylation and NF-κB activation, leading to reduced nitric oxide (NO) and reactive oxygen species (ROS) production. Swertianolin demonstrates potent anti-Helicobacter pylori activity, with an IC50 of 6.1 μM and a minimum bactericidal concentration of 91.7 μM. Additionally, it has been shown to modulate immune function in sepsis, making it applicable for research in Alzheimer's disease, hepatitis B, Helicobacter pylori infections, and sepsis.
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