Biological Activity
AF 12198 is a potent and selective antagonist for the human type I interleukin-1 (IL-1) receptor.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 5.28 mL | 26.38 mL | 52.77 mL |
0.5 mM | 1.06 mL | 5.28 mL | 10.55 mL |
1 mM | 0.53 mL | 2.64 mL | 5.28 mL |
5 mM | 0.11 mL | 0.53 mL | 1.06 mL |
*The above data is based on the productmolecular weight 1895.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17213 |
---|---|
Actions | Antagonist |
CAS No. | 185413-30-3 |
Formula | C96H123N19O22 |
M. Wt | 1895.14 |
Purity | >98% |
Synonyms | AF12198, AF-12198 |
SMILES | C[[email protected]]([[email protected]@H](C(=O)N1CCC[[email protected]]1C(=O)NCC(=O)N[[email protected]@H](CC2=CNC3=CC=CC=C32)C(=O)N[[email protected]@H](CC4=CC=C(C=C4)O)C(=O)N[[email protected]@H](CCC(=O)N)C(=O)N5CC[[email protected]]5C(=O)N[[email protected]@H](CC6=CC=C(C=C6)O)C(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H](CC(C)C)C(=O)N7CCC[[email protected]]7C(=O)N[[email protected]@H](CC(C)C)C(=O)N)NC(=O)[[email protected]](CC8=CNC9=CC=CC=C98)NC(=O)[[email protected]](CCC(=O)O)NC(=O)[[email protected]](CC1=CC=CC=C1)NC(=O)C)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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