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AFB1-FapyGua

Guanine Adduct

AFB1-FapyGua is a prominent guanine adduct formed from the alkylation of nucleic acids by aflatoxin B1 (AFB1). This compound has been shown to exert significant mutagenic effects, making it crucial for studying DNA damage and repair mechanisms. AFB1-FapyGua serves as an important tool in cancer research, particularly in understanding the cellular response to genotoxic stress and the mutational processes involved in tumorigenesis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	65386-83-6
Applications	Guanine Adduct
Formula	C₂₂H₁₉N₅O₉
Molecular Weight	497.41
SMILES	O[C@@H]1[C@@]2([H])C3=C(O[C@@]2([H])O[C@H]1N(C4=C(NC(N)=NC4=O)N)C=O)C=C(OC)C(C5=C6C(CC5)=O)=C3OC6=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.