Fig. 1 · Structure

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Afegostat tartrate

Cat. No. A75221 CAS 919364-56-0

Glucosidase Inhibitor

Afegostat tartrate is a potent glucosidase inhibitor that selectively binds to acid-β-glucosidase (GCase) within the endoplasmic reticulum, functioning as a pharmacological chaperone. This compound enhances enzyme stability and promotes proper folding, making it valuable for research related to Gaucher disease and other lysosomal storage disorders. Its ability to influence GCase activity makes it an important tool for studies aimed at understanding enzyme deficiencies and developing therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 919364-56-0
Applications Glucosidase Inhibitor
Formula C10H19NO9
Molecular Weight 297.26
Synonyms AT 2101; D-Isofagomine tartrate; Isofagomine tartrate
SMILES
OC[C@@H]1[C@H]([C@@H](CNC1)O)O.OC([C@H](O)[C@@H](O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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