Fig. 1 · Structure
Documents & Downloads
Afeletecan
Drug Derivative
Afeletecan is a drug derivative that primarily targets topoisomerase I, an enzyme crucial for DNA replication and transcription. This compound exhibits potent antitumor activity, making it a valuable tool in cancer research. Afeletecan is utilized in studies focused on the mechanisms of chemotherapy and drug resistance, offering insights into potential therapeutic strategies for combating various malignancies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 215604-75-4 |
| Applications | Drug Derivative |
| Formula | C45H49N7O11S |
| Molecular Weight | 895.98 |
| Synonyms | BAY 56-3722 free base; BAY-383441 free base |
| SMILES | O[C@@H]([C@@H]([C@@H]([C@@H](O1)C)O)OC)[C@H]1OC(C=C2)=CC=C2NC(N[C@@H](CC3=CN=CN3)C(N[C@@H](C(C)C)C(O[C@]4(C5=C(COC4=O)C(N6C(C7=NC8=CC=CC=C8C=C7C6)=C5)=O)CC)=O)=O)=S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.