Fig. 1 · Structure

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afi-FSP1-1

FSP1 Inhibitor

Afi-FSP1-1 is a selective inhibitor of Ferroptosis Suppressor Protein 1 (FSP1) with a Ki of 0.283 μM, demonstrating strong binding affinity to the FSP1-FAD-NAD+ complex. This compound effectively induces ferroptosis in cancer cells, making it a valuable tool for studying cancer biology and therapeutic responses. Afi-FSP1-1 is suitable for research applications focused on elucidating the mechanisms of ferroptosis and exploring potential cancer treatment strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3072951-35-7
Applications FSP1 Inhibitor
Formula C25H28N4O2
Molecular Weight 416.52
SMILES
CC1(OCCC2=C1C=CC(C(N3CCC(CC3)C4=NC(C5=CC=CC=C5)=NN4)=O)=C2)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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