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AFP-07 free acid

Catalog No.: A63252
Prostacyclin Receptor Agonist
AFP-07 free acid is a potent and selective agonist of the prostacyclin IP receptor, exhibiting a Ki value of 0.561 nM. This compound is used in research applications related to cardiovascular biology and inflammation, where it may help elucidate the role of prostacyclin signaling in various pathophysiological processes. Its specificity makes AFP-07 free acid a valuable tool for studying the therapeutic potential of prostacyclin modulation in disease models.
AFP-07 free acid 788799-13-3 Prostacyclin Receptor Agonist
Grouped product items
Size Price Stock Qty
500µg
$340.00
In stock
1mg
$660.00
In stock
5mg
$2,830.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAFP-07 free acid is a potent and selective agonist of the prostacyclin IP receptor, exhibiting a Ki value of 0.561 nM. This compound is used in research applications related to cardiovascular biology and inflammation, where it may help elucidate the role of prostacyclin signaling in various pathophysiological processes. Its specificity makes AFP-07 free acid a valuable tool for studying the therapeutic potential of prostacyclin modulation in disease models.
Product Information
Catalog NumA63252
FormulaC22H30F2O5
Molecular Weight412.47
CAS Number788799-13-3
SMILESCCC#CC[C@H](C)[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O/C(C2(F)F)=C\CCCC(O)=O
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GPCR/G Protein > Prostanoid Receptors