AG73 is a polypeptide derived from the G domain of the Laminin α1 chain that functions as a ligand for syndecans. It notably binds to heparin, Syndecan-1, and Syndecan-4, promoting cell adhesion and differentiation, particularly in salivary gland acinar cells. Additionally, AG73 stimulates neurite outgrowth, matrix metalloproteinase secretion, and angiogenesis, retaining its activity even when conjugated to chitosan membranes. This reagent is valuable for research related to melanoma and ischemic injury.
AG73 is a polypeptide derived from the G domain of the Laminin α1 chain that functions as a ligand for syndecans. It notably binds to heparin, Syndecan-1, and Syndecan-4, promoting cell adhesion and differentiation, particularly in salivary gland acinar cells. Additionally, AG73 stimulates neurite outgrowth, matrix metalloproteinase secretion, and angiogenesis, retaining its activity even when conjugated to chitosan membranes. This reagent is valuable for research related to melanoma and ischemic injury.
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