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AGN 191976

Thromboxane Receptor Agonist

AGN 191976 is a selective agonist of the thromboxane A2 (TP) receptor, exhibiting EC50 values of 0.23 nM in rat aorta and 24 nM in human platelets. This compound demonstrates significant intraocular pressure-lowering effects in canine and primate models. AGN 191976 serves as a valuable tool for investigating vascular biology and elucidating the role of thromboxane A2 in vascular function and related pathophysiological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	159359-94-1
Applications	Thromboxane Receptor Agonist
Formula	C₂₁H₃₂O₆
Molecular Weight	380.48
SMILES	O=C(CCC/C=C\C[C@H]1[C@]2(OC(O[C@@]([H])([C@@H]1/C=C/[C@H](CCCCC)O)C2)=O)[H])O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.