AGN 195183

Catalog No.: A16293

RARα agonist

AGN 195183

AGN 195183 Chemical Structure

CAS NO. 367273-07-2

AGN 195183 is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
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Biological Activity

AGN 195183 is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.84 mL 114.19 mL 228.38 mL
0.5 mM 4.57 mL 22.84 mL 45.68 mL
1 mM 2.28 mL 11.42 mL 22.84 mL
5 mM 0.46 mL 2.28 mL 4.57 mL

*The above data is based on the productmolecular weight 437.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16293
Actions Agonist
CAS No. 367273-07-2
Formula C22H22ClF2NO4
M. Wt 437.86
Solubility DMSO
Purity >98%
Synonyms AGN195183, AGN-195183
SMILES CC1(CCC(C2=C1C=C(C(=C2Cl)O)C(=O)NC3=CC(=C(C(=C3)F)C(=O)O)F)(C)C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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