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AGN 196996

RARα antagonist

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Catalog No. A16294

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AGN 196996 5mg A16294-5
$320.00
AGN 196996 10mg A16294-10
$480.00
AGN 196996 50mg A16294-50
$1,400.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).

AGN 196996

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Chemical Information

Catalog Num A16294
Actions Antagonist
M. Wt 482.32
Formula C24H20BrNO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 958295-17-5
Synonyms AGN196996, AGN-196996
SMILES CCOC1=C(C=C(C=C1Br)C(=O)NC2=CC=C(C=C2)C(=O)O)C(=O)C3=CC=C(C=C3)C

Biological Activity

Description
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.73 mL 103.67 mL 207.33mL
0.5 mM 4.15 mL 20.73 mL 41.47 mL
1 mM 2.07 mL 10.37 mL 20.73 mL
5 mM 0.41 mL 2.07 mL 4.15 mL

*The above data is based on the productmolecular weight 482.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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