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AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.73 mL | 103.67 mL | 207.33 mL |
| 0.5 mM | 4.15 mL | 20.73 mL | 41.47 mL |
| 1 mM | 2.07 mL | 10.37 mL | 20.73 mL |
| 5 mM | 0.41 mL | 2.07 mL | 4.15 mL |
*The above data is based on the productmolecular weight 482.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16294 |
|---|---|
| Actions | Antagonist |
| M. Wt | 482.32 |
| Formula | C24H20BrNO5 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 958295-17-5 |
| Synonyms | AGN196996, AGN-196996 |
| SMILES | CCOC1=C(C=C(C=C1Br)C(=O)NC2=CC=C(C=C2)C(=O)O)C(=O)C3=CC=C(C=C3)C |
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