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AGN-242428, also known as VTP-43742, is a potent, selective and orally active RORγt inhibitor for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.09 mL | 90.47 mL | 180.95 mL |
| 0.5 mM | 3.62 mL | 18.09 mL | 36.19 mL |
| 1 mM | 1.81 mL | 9.05 mL | 18.09 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
*The above data is based on the productmolecular weight 552.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16935 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1802706-04-2 |
| Formula | C27H35F3N4O3S |
| M. Wt | 552.65 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | VTP-43742, VTP 43742, VTP43742, AGN242428, AGN 242428 |
| SMILES | CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[[email protected]](C(C)C)N(C[[email protected]]4CC[[email protected]@H](CC4)C(F)(F)F)Cc3c2)nc1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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