AGN-242428

Catalog No.: A16935

RORγt inhibitor

AGN-242428

AGN-242428 Chemical Structure

CAS NO. 1802706-04-2

AGN-242428, also known as VTP-43742, is a potent, selective and orally active RORγt inhibitor for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis.

Availability: In stock

Package Price Qty
1 mg
$800.00
2 mg
$1,500.00
5 mg
$2,700.00
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Biological Activity

AGN-242428, also known as VTP-43742, is a potent, selective and orally active RORγt inhibitor for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.09 mL 90.47 mL 180.95 mL
0.5 mM 3.62 mL 18.09 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.09 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16935
Actions Inhibitor
CAS No. 1802706-04-2
Formula C27H35F3N4O3S
M. Wt 552.65
Solubility DMSO
Purity >98%
Synonyms VTP-43742, VTP 43742, VTP43742, AGN242428, AGN 242428
SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2cnc3[[email protected]](C(C)C)N(C[[email protected]]4CC[[email protected]@H](CC4)C(F)(F)F)Cc3c2)nc1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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